09/03/2002  

SurroMed, Inc. Announces Agreement with PPD Discovery for Cell Surface Target Validation.

Agreement to focus on comparative proteomic and metabolomic analysis of tumor samples.

Mountain View, California (September 30, 2002) - SurroMed, Inc. today announced that it has entered into a service agreement with PPD Discovery, the drug discovery technology subsidiary of PPD, Inc. (Nasdaq: PPDI). Under the terms of the agreement, Menlo Park, Calif.-based PPD Discovery will provide tumor samples for analysis at SurroMed’s Biomarker Discovery Laboratory. Financial terms of the agreement were not disclosed.

SurroMed will analyze the tumor samples using its proprietary integrated mass spectrometry-based platform for proteomic and small organic molecule analysis in order to obtain detailed information concerning the biological makeup of each tumor type. SurroMed will use this data to show the association between certain cell surface proteins identified by PPD Discovery with particular tumor types, which also provides PPD Discovery an ongoing means of demonstrating the functional relevance of its cell surface proteins for tumor growth.

Upon analysis of the data, preferred cell surface proteins will be selected for further study in preclinical in vitro and in vivo models. PPD Discovery will seek to partner its biologically validated cell surface proteins for the development of therapeutic antibodies for prevention of tumor growth.

"We are delighted to have the opportunity to collaborate with PPD Discovery." said Gordon Ringold, Ph.D., CEO and Chairman of SurroMed. "Our quantitative differential protein and small organic molecule profiling capabilities provide a unique combination of sensitivity, throughput and reproducibility that enable rapid and effective biomarker identification. We will use our capabilities to validate certain cancer targets identified by PPD Discovery."

About SurroMed, Inc.
Headquartered in Mountain View, California, SurroMed is pioneering biomarker enabled drug discovery and development. The Company focuses on discovering and applying biomarkers to improve the drug discovery and development process and enable the precise diagnosis and personalized treatment of disease. SurroMed’s research process yields biological markers and information that enable accelerated, cost-efficient discovery and development of new therapeutic products, as well as development of diagnostic tests for early disease detection, disease staging, patient stratification, and guiding and monitoring therapy.

Contacts:

SurroMed, Inc.
August J. Moretti
CFO and General Counsel
(650) 230-1961
email: [email protected]

Noonan/Russo Communications, Inc.

Ian R. McConnell
Senior Account Executive
415) 677-4455 ext. 233
email: [email protected]

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